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. 2013 Dec;11(12):2187-9.
doi: 10.1111/jth.12423.

The contribution of red blood cells to thrombin generation in sickle cell disease: meizothrombin generation on sickled red blood cells

M F Whelihan  1 , M J Mooberry, V Zachary, R L Bradford, K I Ataga, K G Mann, N S Key
Affiliations

The contribution of red blood cells to thrombin generation in sickle cell disease: meizothrombin generation on sickled red blood cells

M F Whelihan et al. J Thromb Haemost. 2013 Dec.
No abstract available

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Conflict of interest statement

Conflicts of Interest Disclosure: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
αTAT and mTAT ELISA analyses of HbSS and Control groups. Whole blood was drawn into 0.1 mg/mL CTI and activated by 5 pM TF at t=0. Samples were quenched at varying intervals with EDTA and FPR-chloromethyl ketone prior to being analyzed by αTAT and mTAT ELISA assays. A. Average αTAT generation profiles for healthy African American controls (N=6) (▲) and for HbSS patients (N=7)( formula image). B. Average mTAT generation profiles for healthy African American controls (N=6)(▲) and for HbSS patients (N=7) ( formula image). Data are shown as the mean±SEM.
See this image and copyright information in PMC

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