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Comparative Study
. 1975 Sep;19(5):426-31.

Phagocytosis of Coxiella burneti by macrophages

J Kazár, E Skultétyová, R Brezina
  • PMID: 241247
Comparative Study

Phagocytosis of Coxiella burneti by macrophages

J Kazár et al. Acta Virol. 1975 Sep.

Abstract

Live or killed purified phase I and phase II Coxiella burneti organisms were phagocytized to a similar extent by mouse or guinea pig peritoneal macrophages and polymorphonuclear leukocytes (PMN); phase II was much more susceptible to phagocytosis than phase I. Phagocytosis of phase I was enhanced only by immune sera containing phase I antibodies. Increased in vivo phagocytosis of phase I organisms by macrophages from animals immunized with live phase I C. burneti was lost following their in vitro cultivation and washing.

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