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. 1985;16(4):335-9.
doi: 10.1016/0306-3623(85)90192-2.

Relation between inhibition of calmodulin and mediator release from rat mast cells

K Ohishi, T Suzuki, M K Uchida

Relation between inhibition of calmodulin and mediator release from rat mast cells

K Ohishi et al. Gen Pharmacol. 1985.

Abstract

Cationic drugs that interact with calmodulin such as chlorpromazine, trifluoperazine, W-7 and lidocaine caused dose-dependent release of mediator from rat mast cells. A significant correlation was observed between the effects of test drugs with different structure in causing mediator release and calmodulin inhibition.

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