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. 2013 Dec 4;49(93):10947-9.
doi: 10.1039/c3cc45502e.

A multicomponent cascade reaction for the synthesis of novel chromenopyranpyrazole scaffolds

Manickam Bakthadoss  1 , Damodharan Kannan, Raman Selvakumar
Affiliations

A multicomponent cascade reaction for the synthesis of novel chromenopyranpyrazole scaffolds

Manickam Bakthadoss et al. Chem Commun (Camb). .

Abstract

A catalyst, solvent, work-up and column free synthesis of chromenopyranpyrazoles via multicomponent cascade reaction has been achieved with high stereoselectivity. This novel reaction creates two N-C, two C-C and one O-C bonds through a domino process for the construction of three new rings and three contiguous stereogenic centers.

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