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. 2013 Dec 4;49(93):10980-2.
doi: 10.1039/c3cc45649h.

Bispidine as a helix inducing scaffold: examples of helically folded linear peptides

V Haridas  1 , Sandhya Sadanandan, M V S Gopalakrishna, M B Bijesh, Ram P Verma, Srinivas Chinthalapalli, Ashutosh Shandilya
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Bispidine as a helix inducing scaffold: examples of helically folded linear peptides

V Haridas et al. Chem Commun (Camb). .

Abstract

We designed and synthesized bispidine-anchored peptides and showed that these peptides as small as (containing four chiral α-amino acid residues) adopt a right handed helical conformation. Bispidine anchored linear peptide adopts a helical conformation in solution and in the solid state.

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