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. 2013 Oct 16;5(207):207ps14.
doi: 10.1126/scitranslmed.3006305.

Going with the flow: from circulating tumor cells to DNA

Francois-Clement Bidard  1 , Britta Weigelt, Jorge S Reis-Filho
Affiliations

Going with the flow: from circulating tumor cells to DNA

Francois-Clement Bidard et al. Sci Transl Med. .

Abstract

Molecular analyses of circulating tumor DNA (ctDNA) in plasma from cancer patients have the potential to deliver minimally invasive diagnostic and disease-monitoring biomarkers. Drawing from experience gained through the translation of circulating tumor cell detection to clinical tests, we discuss ctDNA as a source of tumor material for biomarker development.

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