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Review
. 2013 Jul 30;47(3):206-18.
doi: 10.2478/raon-2013-0007.

Comparison between whole-body MRI and Fluorine-18-Fluorodeoxyglucose PET or PET/CT in oncology: a systematic review

Mario Ciliberto  1 , Fabio Maggi, Giorgio Treglia, Federico Padovano, Lucio Calandriello, Alessandro Giordano, Lorenzo Bonomo
Affiliations
Review

Comparison between whole-body MRI and Fluorine-18-Fluorodeoxyglucose PET or PET/CT in oncology: a systematic review

Mario Ciliberto et al. Radiol Oncol. .

Abstract

Background: The aim of the article is to systematically review published data about the comparison between positron emission tomography (PET) or PET/computed tomography (PET/CT) using Fluorine-18-Fluorodeoxyglucose (FDG) and whole-body magnetic resonance imaging (WB-MRI) in patients with different tumours.

Methods: A comprehensive literature search of studies published in PubMed/MEDLINE, Scopus and Embase databases through April 2012 and regarding the comparison between FDG-PET or PET/CT and WB-MRI in patients with various tumours was carried out.

Results: Forty-four articles comprising 2287 patients were retrieved in full-text version, included and discussed in this systematic review. Several articles evaluated mixed tumours with both diagnostic methods. Concerning the specific tumour types, more evidence exists for lymphomas, bone tumours, head and neck tumours and lung tumours, whereas there is less evidence for other tumour types.

Conclusions: Overall, based on the literature findings, WB-MRI seems to be a valid alternative method compared to PET/CT in oncology. Further larger prospective studies and in particular cost-effectiveness analysis comparing these two whole-body imaging techniques are needed to better assess the role of WB-MRI compared to FDG-PET or PET/CT in specific tumour types.

Keywords: PET/CT; diffusion-weighted imaging; fluorodeoxyglucose; oncology; positron emission tomography; whole-body magnetic resonance imaging.

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Figures

FIGURE 1.
FIGURE 1.
Flow chart of the search for eligible studies on the comparison of FDG-PET or PET/CT and WB-MRI in oncology.
See this image and copyright information in PMC

References

    1. Hodolic M. Role of F-18-choline PET/CT in evaluation of patients with prostate carcinoma. Radiol Oncol. 2011;45:17–21. - PMC - PubMed
    1. Basu S, Alavi A. Unparalleled contribution of 18F-FDG PET to medicine over 3 decades. J Nucl Med. 2008;49:17N–21N. 37N. - PubMed
    1. Wang X, Xu M, Liang H, Xu LS. Comparison of CT and MRI in diagnosis of cerebrospinal leak induced by multiple fractures of skull base. Radiol Oncol. 2011;45:91–6. - PMC - PubMed
    1. Schmidt GP, Reiser MF, Baur-Melnyk A. Whole-body MRI for the staging and follow-up of patients with metastasis. Eur J Radiol. 2009;70:393–400. - PubMed
    1. Lambregts DM, Maas M, Cappendijk VC, Prompers LM, Mottaghy FM, Beets GL, et al. Whole-body diffusion-weighted magnetic resonance imaging: Current evidence in oncology and potential role in colorectal cancer staging. Eur J Cancer. 2011;47:2107–16. - PubMed

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