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Case Reports
. 2013 Oct;55(5):e111-5.
doi: 10.1111/ped.12130.

Thrombolytic therapy in Kawasaki disease: a report of four cases

Mana Harada  1 , Katsumi Akimoto, Masao Otaka, Keiko Sato, Hisayuki Oda, Masahiro Otsuki, Ken Takahashi, Masahiko Kishiro, Toshiaki Shimizu
Affiliations
Case Reports

Thrombolytic therapy in Kawasaki disease: a report of four cases

Mana Harada et al. Pediatr Int. 2013 Oct.

Abstract

Four patients with a thrombus in a coronary artery aneurysm due to Kawasaki disease (KD) were treated at our hospital between 1994 and 2009. All the cases were treated with intravenous coronary thrombolysis (IVCT) therapy and the cases with acute myocardial infarction were treated with additional intracoronary thrombolysis therapy. Although both thrombolytic therapies were effective, IVCT required more time than intracoronary thrombolysis to resolve the thrombus. We concluded that IVCT can be used as the first-line thrombolytic therapy for KD, except in cases with acute myocardial infarction.

Keywords: Kawasaki disease; acute myocardial infarction; intracoronary thrombolysis; intravenous coronary thrombolysis; tissue polypeptide antigen.

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