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. 2013 Jul-Sep;11(3):345-9.
doi: 10.1590/s1679-45082013000300014.

Clinical evolution of mediastinitis in patients undergoing adjuvant hyperbaric oxygen therapy after coronary artery bypass surgery

[Article in English, Portuguese]
Julyana Galvão Tabosa do Egito, Cely Saad Abboud, Aline Pâmela Vieira de Oliveira, Carlos Alberto Gonçalves Máximo, Carolina Moreira Montenegro, Vivian Lerner Amato, Roberto Bammann, Pedro Silvio Farsky

Clinical evolution of mediastinitis in patients undergoing adjuvant hyperbaric oxygen therapy after coronary artery bypass surgery

[Article in English, Portuguese]
Julyana Galvão Tabosa do Egito et al. Einstein (Sao Paulo). 2013 Jul-Sep.

Abstract
in English, Portuguese

Objective: To evaluate the use of hyperbaric oxygen therapy as an adjunctive treatment in mediastinitis after coronary artery bypass surgery.

Methods: This is a retrospective descriptive study, performed between October 2010 and February 2012. Hyperbaric oxygen therapy was indicated in difficult clinical management cases despite antibiotic therapy.

Results: We identified 18 patients with mediastinitis during the study period. Thirty three microorganisms were isolated, and polymicrobial infection was present in 11 cases. Enterobacteriaceae were the most prevalent pathogens and six were multi-resistant agents. There was only 1 hospital death, 7 months after the oxygen therapy caused by sepsis, unrelated to hyperbaric oxygen therapy. This treatment was well-tolerated.

Conclusion: The initial data showed favorable clinical outcomes.

Objetivo:: Avaliação da utilização de oxigenoterapia hiperbárica, como tratamento adjuvante, em casos de mediastinite, em pós-operatório de cirurgia de revascularização miocárdica.

Métodos:: Estudo descritivo retrospectivo, no período entre outubro de 2010 e fevereiro de 2012. A oxigenoterapia hiperbárica foi indicada nos casos de difícil manejo clínico a despeito da antibioticoterapia.

Resultados:: Identificaram-se 18 pacientes com mediastinite, nos quais 33 microrganismos foram isolados, estando a infecção polimicrobiana presente em 11 casos. Enterobactérias foram os germes mais prevalentes e seis agentes multirresistentes. Ocorreu 1 óbito, na evolução, 7 meses após o término da oxigenoterapia, por septicemia, não relacionado à terapêutica. O tratamento foi bem tolerado.

Conclusão:: Os resultados clínicos iniciais foram favoráveis.

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Conflict of interest statement

Conflits of interest: none.

Figures

Figure 1
Figure 1. Clinical evolution of surgical wound after nine HBO sessions associated with antibiotic therapy
See this image and copyright information in PMC

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