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. 2013 Aug;6(2):562-564.
doi: 10.3892/ol.2013.1378. Epub 2013 Jun 6.

Perforated sarcomatoid carcinoma of the jejunum: Case report

Ning Han  1 , Qing-Hui Han, Yang-Zhou Liu, Zeng-Chun Li, Jiao Li
Affiliations

Perforated sarcomatoid carcinoma of the jejunum: Case report

Ning Han et al. Oncol Lett. 2013 Aug.

Abstract

Sarcomatoid carcinomas exhibit features that are common to epithelial and mesenchymal tumors. These carcinomas are rare, particularly in the small intestine. In the current case report, we describe a case of an intestinal sarcomatoid carcinoma in a 70-year-old Chinese female. Sarcomatoid carcinoma was confirmed based on light microscopy and immunohistochemical observations. The patient presented with symptoms of acute abdomen, which was due to an intestinal perforation caused by sarcomatoid carcinoma of the small bowel. Patients with sarcomatoid carcinoma are usually associated with a poor prognosis. However, this patient experienced a relatively favorable prognosis, which may be attributed to low positivity for Ki67 in the tumor.

Keywords: perforation; sarcomatoid carcinoma; small intestine.

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Figures

Figure 1.
Figure 1.
Portion of the jejunum with perforation. The intestinal wall was thickened and inflexible with a 0.1×0.1-cm perforation (indicated by an asterisk).
Figure 2.
Figure 2.
Spindle-shaped cells were present in the tumor, as well as hyper-chromatic nuclei and atypical mitotic features (staining, hematoxylin and eosin; magnification, ×200).
Figure 3.
Figure 3.
Tumor cells were markedly positive for vimentin by immunohistochemistry (staining, EnVision™ two-step method; magnification, ×200).
Figure 4.
Figure 4.
Tumor cells were markedly positive for pan-cytokeratin (CK) by immunohistochemistry (staining, EnVision™ two-step method; magnification, ×200).
See this image and copyright information in PMC

References

    1. Reid-Nicholson M, Idrees M, Perino G, Hytiroglou P. Sarcomatoid carcinoma of the small intestine: A case report and review of the literature. Arch Pathol Lab Med. 2004;128:918–921. - PubMed
    1. Ozturk E, Yilmazlar T, Yerci O. A rare tumor located in the anorectal junction: Sarcomatoid carcinoma. Turk J Gastroenterol. 2006;17:236–239. - PubMed
    1. Yucel AF, Kocakusak A, Arikan S, Demirbag N, Tarlaci A, Batur S. A rare cause of acute abdomen: Perforated primary sarcomatoid carcinoma of the small intestine - report of a case, with a brief review of the literature. J Cancer Res Ther. 2011;7:348–350. - PubMed
    1. Conzo G, Giordano A, Candela G, Insabato L, Santini L. Colonic carcinosarcoma. J Gastroenterol Hepatol. 2003;18:748–749. - PubMed
    1. Ishida H, Ohsawa T, Nakada H, Hashimoto D, Ohkubo T, Adachi A, Itoyama S. Carcinosarcoma of the rectosigmoid colon: Report of a case. Surg Today. 2003;33:545–549. - PubMed

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