Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2013 Sep 3;110(36):E3371.
doi: 10.1073/pnas.1307452110.

Reply to Osterburg et al.: To study human inflammatory diseases in humans

Ronald G Tompkins, H Shaw Warren, Michael N Mindrinos, Wenzhong Xiao, Ronald W Davis
Comment

Reply to Osterburg et al.: To study human inflammatory diseases in humans

Ronald G Tompkins et al. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Comment on

  • Genomic responses in mouse models poorly mimic human inflammatory diseases.
    Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Jeschke MG, Klein MB, Gamelli RL, Gibran NS, Brownstein BH, Miller-Graziano C, Calvano SE, Mason PH, Cobb JP, Rahme LG, Lowry SF, Maier RV, Moldawer LL, Herndon DN, Davis RW, Xiao W, Tompkins RG; Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. Seok J, et al. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3507-12. doi: 10.1073/pnas.1222878110. Epub 2013 Feb 11. Proc Natl Acad Sci U S A. 2013. PMID: 23401516 Free PMC article. Clinical Trial.
  • Concerns over interspecies transcriptional comparisons in mice and humans after trauma.
    Osterburg AR, Hexley P, Supp DM, Robinson CT, Noel G, Ogle C, Boyce ST, Aronow BJ, Babcock GF. Osterburg AR, et al. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):E3370. doi: 10.1073/pnas.1306033110. Epub 2013 Jul 11. Proc Natl Acad Sci U S A. 2013. PMID: 23847210 Free PMC article. No abstract available.

References

    1. Osterburg AR, et al. Concerns over interspecies transcriptional comparisons in mice and humans after trauma. Proc Natl Acad Sci USA. 2013;110:E3370. - PMC - PubMed
    1. Seok J, et al. Inflammation and Host Response to Injury, Large Scale Collaborative Research Program Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci USA. 2013;110(9):3507–3512. - PMC - PubMed
    1. De Maio A, Mooney ML, Matesic LE, Paidas CN, Reeves RH. Genetic component in the inflammatory response induced by bacterial lipopolysaccharide. Shock. 1998;10(5):319–323. - PubMed
    1. Storey JD, Xiao W, Leek JT, Tompkins RG, Davis RW. Significance analysis of time course microarray experiments. Proc Natl Acad Sci USA. 2005;102(36):12837–12842. - PMC - PubMed

LinkOut - more resources