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Review
. 2013 Sep-Nov;28(5-6):275-80.
doi: 10.3109/08820538.2013.825295.

The genetics of keratoconus

Han-Ying Peggy Chang  1 , James Chodosh
Affiliations
Review

The genetics of keratoconus

Han-Ying Peggy Chang et al. Semin Ophthalmol. 2013 Sep-Nov.

Abstract

Keratoconus is a bilateral, non-inflammatory corneal ectasia characterized by progressive conical thinning and protrusion of the cornea. Its etiology has long been believed to be multifactorial, with environmental, behavioral, and genetic factors all contributing to the disease process. This review focuses specifically on examining the evidence that supports a genetic basis for keratoconus.

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