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Review
. 2013 Oct 16;14(4):374-8.
doi: 10.1016/j.chom.2013.09.011.

Is RNA interference a physiologically relevant innate antiviral immune response in mammals?

Bryan R Cullen  1 , Sara Cherry, Benjamin R tenOever
Affiliations
Free article
Review

Is RNA interference a physiologically relevant innate antiviral immune response in mammals?

Bryan R Cullen et al. Cell Host Microbe. .
Free article

Abstract

While RNA interference (RNAi) functions as an antiviral response in plants, nematodes, and arthropods, a similar antiviral role in mammals has remained controversial. Three recent papers provide evidence that either favors or challenges this hypothesis. Here, we discuss these new findings in the context of previous research.

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