Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Sep;46(5):450-5.
doi: 10.5946/ce.2013.46.5.450. Epub 2013 Sep 30.

Endoscopic treatment for early foregut neuroendocrine tumors

Affiliations
Review

Endoscopic treatment for early foregut neuroendocrine tumors

Moo In Park. Clin Endosc. 2013 Sep.

Abstract

Foregut neuroendocrine tumors (NETs) include those arising in the esophagus, stomach, pancreas, and duodenum and seem to have a broad range of clinical behavior from benign to metastatic. Several factors including the advent of screening endoscopy may be related to increased incidence of gastrointestinal NETs; thus, many foregut NETs are diagnosed at an early stage. Early foregut NETs, such as those of the stomach and duodenum, can be managed with endoscopic treatment because of a low frequency of lymph node and distant metastases. However, controversy continues concerning the optimal management of early foregut NETs due to a lack of controlled prospective studies. Several issues such as indications, technical issues, and outcomes of endoscopic treatment for early foregut NETs are reviewed based on some published studies.

Keywords: Duodenum; Endoscopic treatment; Neuroendocrine tumors; Stomach.

PubMed Disclaimer

Conflict of interest statement

The author has no financial conflicts of interest.

Figures

Fig. 1
Fig. 1
Management of gastric carcinoids according to European Neuroendocrine Tumor Society (ENETS) guidelines. Adapted from Nikou et al. Gastroenterol Res Pract 2012;2012:287825.

Similar articles

Cited by

References

    1. Li QL, Zhang YQ, Chen WF, et al. Endoscopic submucosal dissection for foregut neuroendocrine tumors: an initial study. World J Gastroenterol. 2012;18:5799–5806. - PMC - PubMed
    1. Klimstra DS, Modlin IR, Coppola D, Lloyd RV, Suster S. The pathologic classification of neuroendocrine tumors: a review of nomenclature, grading, and staging systems. Pancreas. 2010;39:707–712. - PubMed
    1. Rindi G, Arnold R, Bosman FT, et al. The International Agency for Research on Cancer, editors. Nomenclature and classification of neuroendocrine neoplasms of the digestive system. In: Bosman TF, Carneiro F, Hruban RH, Theise ND, editors. WHO Classification of Tumours of the Digestive System. 4th ed. Lyon: International Agency for Research on Cancer; 2010. p. 13.
    1. Hruban RH, Pitman MB, Klimstra DS American Registry of Pathology; Armed Forces Institute of Pathology (U.S.) Tumors of the Pancreas. Washington DC: American Registry of Pathology in collaboration with the Armed Forces Institute of Pathology; 2007. p. 422.
    1. Yao JC, Hassan M, Phan A, et al. One hundred years after "carcinoid": epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States. J Clin Oncol. 2008;26:3063–3072. - PubMed

LinkOut - more resources