Role of developmental overnutrition in pediatric obesity and type 2 diabetes
- PMID: 24147926
- DOI: 10.1111/nure.12061
Role of developmental overnutrition in pediatric obesity and type 2 diabetes
Abstract
Childhood obesity continues to be a significant public health burden. Empirical evidence has begun to identify intrauterine and postnatal pathways that increase the likelihood of excess adiposity and increased risk of type 2 diabetes among offspring. Reviewed here is the evidence supporting a transgenerational vicious cycle that increases obesity and diabetes in offspring and contributes substantially to the increases in obesity and type 2 diabetes observed over the past several decades. The public health impact of these findings is discussed and future research opportunities are outlined.
Keywords: childhood obesity; developmental overnutrition; pediatrics; type 2 diabetes.
© 2013 International Life Sciences Institute.
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