Current opinions on tendinopathy
- PMID: 24149868
- PMCID: PMC3761855
Current opinions on tendinopathy
Abstract
Tendinopathy is characterized by pain in the tendon and impaired performance sometimes associated with swelling of the tendon. Its diagnosis is usually clinical but ultrasonography and magnetic resonance imaging can refine the diagnosis. Tendinopathy is highly prevalent and is one of the most frequently self reported musculoskeletal diseases in physical workers and sports people. Nevertheless, it is very difficult to carry out general epidemiologic studies on tendinopathy because of the varying sports cultures and sports habits in different countries. The aetiology of tendinopathy seems to be multi-factorial, involving intrinsic and extrinsic factors. The role of inflammation is still debated but the absence of inflammatory cells does not mean that inflammatory mediators are not implicated. Different theories have been advanced to explain pain and chronicity mechanisms, but these mechanisms remain largely unknown. "Conventional "treatments are generally employed empirically to fight pain and inflammation but they do not modify the histological structure of the tendon. However, these treatments are not completely satisfactory and the recurrence of symptoms is common. Currently, eccentric training remains the treatment of choice for tendinopathy, even though some studies are contradictory. Moreover, many interesting new treatments are now being developed to treat tendinopathy, but there is little evidence to support their use in clinical practice. Key pointsThe word "tendinopathy "is the correct term for the clinical diagnosis of pain accompanied by impaired performance, and sometimes swelling in the tendon.The aetiology of tendinopathy seems to be a multi-factorial process, involving promoting factors that are intrinsic or extrinsic, working either alone or in combination.US (with color Doppler) and MRI are usually prescribed when tendinopathy is unresponsive to treatment and entails lingering symptoms.Eccentric training is currently considered to be the most efficient treatment for tendinopathy; nevertheless, in order to be effective, this treatment needs specific modalities: slow speed, low intensity and gradual intensification, with minimum 20 to 30 sessions of exercises often being needed.Many interesting new treatments are now being developed to treat tendinopathy, but currently there is little evidence to support their use in clinical practice.
Keywords: Aetiology; epidemiology; inflammation; tendinopathy; therapeutic advances; treatments.
Figures
Similar articles
-
[Midportion Achilles tendinopathy].Unfallchirurg. 2017 Dec;120(12):1038-1043. doi: 10.1007/s00113-017-0411-5. Unfallchirurg. 2017. PMID: 28921035 Review. German.
-
Injection with autologous conditioned serum has better clinical results than eccentric training for chronic Achilles tendinopathy.Knee Surg Sports Traumatol Arthrosc. 2019 Sep;27(9):2744-2753. doi: 10.1007/s00167-019-05465-8. Epub 2019 Mar 21. Knee Surg Sports Traumatol Arthrosc. 2019. PMID: 30900032
-
Effect of High-Volume Injection, Platelet-Rich Plasma, and Sham Treatment in Chronic Midportion Achilles Tendinopathy: A Randomized Double-Blinded Prospective Study.Am J Sports Med. 2017 Jul;45(9):2034-2043. doi: 10.1177/0363546517702862. Epub 2017 May 22. Am J Sports Med. 2017. PMID: 28530451 Clinical Trial.
-
Heavy Slow Resistance Versus Eccentric Training as Treatment for Achilles Tendinopathy: A Randomized Controlled Trial.Am J Sports Med. 2015 Jul;43(7):1704-11. doi: 10.1177/0363546515584760. Epub 2015 May 27. Am J Sports Med. 2015. PMID: 26018970 Clinical Trial.
-
Patellar Tendinopathy: Clinical Diagnosis, Load Management, and Advice for Challenging Case Presentations.J Orthop Sports Phys Ther. 2015 Nov;45(11):887-98. doi: 10.2519/jospt.2015.5987. Epub 2015 Sep 21. J Orthop Sports Phys Ther. 2015. PMID: 26390269 Review.
Cited by
-
Astym treatment vs. eccentric exercise for lateral elbow tendinopathy: a randomized controlled clinical trial.PeerJ. 2015 May 19;3:e967. doi: 10.7717/peerj.967. eCollection 2015. PeerJ. 2015. PMID: 26038722 Free PMC article.
-
Effect of Nutraceutical Factors on Hepatic Intermediary Metabolism in Wistar Rats with Induced Tendinopathy.Int J Mol Sci. 2024 Jan 3;25(1):629. doi: 10.3390/ijms25010629. Int J Mol Sci. 2024. PMID: 38203800 Free PMC article.
-
Species variations in tenocytes' response to inflammation require careful selection of animal models for tendon research.Sci Rep. 2021 Jun 14;11(1):12451. doi: 10.1038/s41598-021-91914-9. Sci Rep. 2021. PMID: 34127759 Free PMC article.
-
Antifibrotic and Pro-regenerative Effects of SMAD3 siRNA and Collagen I mRNA-Loaded Lipid Nanoparticles in Human Tenocytes.ACS Appl Nano Mater. 2024 Jul 18;7(15):17736-17747. doi: 10.1021/acsanm.4c02996. eCollection 2024 Aug 9. ACS Appl Nano Mater. 2024. PMID: 39144399 Free PMC article.
-
Farrerol alleviates collagenase-induced tendinopathy by inhibiting ferroptosis in rats.J Cell Mol Med. 2022 Jun;26(12):3483-3494. doi: 10.1111/jcmm.17388. Epub 2022 May 18. J Cell Mol Med. 2022. PMID: 35582962 Free PMC article.
References
-
- Ackermann P.W., Salo P.T., Hart D.A. (2009) Neuronal pathways in tendon healing. Fronties in Bioscience 14, 5165-5187 - PubMed
-
- Alfredson H. (2005) Conservative management of Achilles tendinopathy: new ideas. Foot and ankle clinics 10, 321-329 - PubMed
-
- Alfredson H., Harstad H., Haugen S., Ohberg L. (2006) Sclerosing polidocanol injections to treat chronic painful shoulder impingement syndrome-results of a two-centre collaborative pilot study. Knee Surgery, Sports Traumatology, Arthroscopy 14, 1321-1326 - PubMed
-
- Alfredson H., Ohberg L. (2006) Increased intratendinous vascularity in the early period after sclerosing injection treatment in Achilles tendinosis : a healing response? Knee Surgery, Sports Traumatology, Arthroscopy 14, 399-401 - PubMed
-
- Allison G.T., Purdam C. (2009) Eccentric loading for Achilles tendinopathy--strengthening or stretching? British Journal of Sports Medicine 43, 276-279 - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical