Teleocidin, a tumour promoter, stimulates synthesis of primate retroviruses in persistently infected human cells
- PMID: 2415081
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Teleocidin, a tumour promoter, stimulates synthesis of primate retroviruses in persistently infected human cells
Arch Geschwulstforsch.
1985.
Abstract
The naturally occurring tumour promoter teleocidin produces a pronounced but transient enhancement of the synthesis of extracellular viral particles in human cells chronically infected with simian retroviruses of type C (baboon endogenous virus, simian sarcoma virus) or type D (Mason-Pfizer monkey virus) or a human cell line-derived type D isolate (PMF virus), respectively. The retrovirus-stimulating activity of teleocidin is very similar to that previously described for the tumour-promoting phorbol ester TPA in the same cell systems.
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