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Review
. 2013 Sep 23;10(12):1649-57.
doi: 10.7150/ijms.6395. eCollection 2013.

Mammalian sperm fertility related proteins

Ali Ashrafzadeh  1 , Saiful Anuar Karsani, Sheila Nathan
Affiliations
Review

Mammalian sperm fertility related proteins

Ali Ashrafzadeh et al. Int J Med Sci. .

Abstract

Infertility is an important aspect of human and animal reproduction and still presents with much etiological ambiguity. As fifty percent of infertility is related to the male partner, molecular investigations on sperm and seminal plasma can lead to new knowledge on male infertility. Several comparisons between fertile and infertile human and other species sperm proteome have shown the existence of potential fertility markers. These proteins have been categorized into energy related, structural and other functional proteins which play a major role in sperm motility, capacitation and sperm-oocyte binding. The data from these studies show the impact of sperm proteome studies on identifying different valuable markers for fertility screening. In this article, we review recent development in unraveling sperm fertility related proteins.

Keywords: fertility; infertility.; protein; proteomics; sperm.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

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