Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Nov;13(8):779-88.
doi: 10.1586/14737159.2013.848794.

The FilmArray® respiratory panel: an automated, broadly multiplexed molecular test for the rapid and accurate detection of respiratory pathogens

N Esther Babady  1
Affiliations
Review

The FilmArray® respiratory panel: an automated, broadly multiplexed molecular test for the rapid and accurate detection of respiratory pathogens

N Esther Babady. Expert Rev Mol Diagn. 2013 Nov.

Abstract

The FilmArray Respiratory Panel (RP) (BioFire(™) Diagnostics, Inc., Salt Lake City, UT, USA) is the first multiplex molecular panel cleared by the US FDA for the detection of both bacterial and viral respiratory pathogens in nasopharygeal swabs. The FilmArray RP targets 20 pathogens including 17 viruses and subtypes and three bacteria, and is performed with minimal sample manipulation. The FilmArray RP has a fully automated sample-to-answer workflow with a turn-around-time of approximately 1 h. The reported sensitivity and specificity of the assay ranges from 80 to 100 and 100%, respectively, with the sensitivity for the adenovirus as low as 46%. A new version of the FilmArray RP assay (version 1.7) with improved sensitivity for the adenovirus was released in 2013. The performance characteristics and simplified workflow have allowed its implementation in a wide range of laboratories. The FilmArray RP has changed the diagnostic landscape and will have a significant impact on the care of patients with respiratory tract infection.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
The FilmArray instrument and pouch.
See this image and copyright information in PMC

References

    1. Woodwell DA, Cherry DK. National ambulatory medical care survey: 2002 summary. Adv. Data. (346), 1–44 (2004). - PubMed
    1. Juven T, Mertsola J, Waris M et al. Etiology of community-acquired pneumonia in 254 hospitalized children. Pediatr. Infect. Dis. J. 19(4), 293–298 (2000). - PubMed
    1. Koskenvuo M, Mottonen M, Rahiala J et al. Respiratory viral infections in children with leukemia. Pediatr. Infect. Dis. J. 27(11), 974–980 (2008). - PubMed
    1. Ginocchio CC, Zhang F, Manji R et al. Evaluation of multiple test methods for the detection of the novel 2009 influenza A (H1N1) during the New York City outbreak. J. Clin. Virol. 45(3), 191–195 (2009). - PMC - PubMed
    1. Lee JW, Kang HJ, Park JD, Shin HY, Ahn HS. Early pulmonary complications after hematopoietic stem cell transplantation in pediatric patients: association with cytomegalovirus infection. J. Pediatr. Hematol. Oncol. 31(8), 545–551 (2009). - PubMed

MeSH terms

Substances