Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Nov 22;76(11):2040-6.
doi: 10.1021/np400296s. Epub 2013 Oct 23.

Withanolide artifacts formed in methanol

Cong-Mei Cao  1 , Huaping Zhang, Robert J Gallagher, Barbara N Timmermann
Affiliations

Withanolide artifacts formed in methanol

Cong-Mei Cao et al. J Nat Prod. .

Abstract

Methanol solutions of the main withanolides (6-8) naturally present in Physalis longifolia yielded five artificial withanolides (1-5), including three new compounds (1-3). Withanolides 1 and 2 were identified as intramolecular Michael addition derivatives, while withanolides 3-5 were the result of intermolecular Michael addition. A comprehensive literature investigation was conducted to identify potential withanolide Michael addition artifacts isolated from Solanaceous species to date.

PubMed Disclaimer

Publication types

MeSH terms

Substances

LinkOut - more resources