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. 2013 Nov 19;81(21):1864-8.
doi: 10.1212/01.wnl.0000436074.98534.6e. Epub 2013 Oct 23.

Spinal cord injury and type 2 diabetes: results from a population health survey

Jacquelyn J Cragg  1 , Vanessa K Noonan, Marcel Dvorak, Andrei Krassioukov, G B John Mancini, Jaimie F Borisoff
Affiliations

Spinal cord injury and type 2 diabetes: results from a population health survey

Jacquelyn J Cragg et al. Neurology. .

Abstract

Objective: The objective of this study was to evaluate the association between spinal cord injury (SCI) and type 2 diabetes in a large representative sample and to determine whether an association exists irrespective of known risk factors for type 2 diabetes.

Methods: Data were obtained on 60,678 respondents to the Statistics Canada 2010 Cycle of the cross-sectional Canadian Community Health Survey. Multivariable logistic regression, incorporating adjustment for confounders and probability weights to account for the Canadian Community Health Survey sampling method, was conducted to quantify this association.

Results: After adjustment for both sex and age, SCI was associated with a significant increased odds of type 2 diabetes (adjusted odds ratio = 1.66, 95% confidence interval 1.16-2.36). These heightened odds persisted after additional adjustment for smoking status, hypertension status, body mass index, daily physical activity, alcohol intake, and daily consumption of fruits and vegetables (fully adjusted odds ratio = 2.45, 95% confidence interval 1.34-4.47).

Conclusions: There is a strong association between SCI and type 2 diabetes, which is not explained by known risk factors for type 2 diabetes.

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Figures

Figure
Figure. Grouped bar plot of prevalence of type 2 diabetes
Weighted prevalence (%) of type 2 diabetes is shown separately for the spinal cord injury (SCI) group (green bars) and non-SCI group (orange bars) for each age category.
See this image and copyright information in PMC

Comment in

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