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Case Reports
. 2013 Jun;54(6):602-5.

Primary central nervous system T-cell lymphoma mimicking meningoencephalomyelitis in a cat

Silvia Guil-Luna  1 , Librado Carrasco, Jaime Gómez-Laguna, Monika Hilbe, Juan J Mínguez, Kernt Köhler, Juana Martín de las Mulas
Affiliations
Case Reports

Primary central nervous system T-cell lymphoma mimicking meningoencephalomyelitis in a cat

Silvia Guil-Luna et al. Can Vet J. 2013 Jun.

Abstract
in English, French

A cat was presented with right head tilt and circling. The lack of expression of virus antigens did not support the postmortem diagnosis of encephalomyelitis pointing to a diffuse primary central nervous system T-cell lymphoma on the basis of CD3 and CD45R co-expression with absence of CD79α staining.

Lymphome primaire de système nerveux central type T imitant méningo-encéphalomyélite chez un chat. Un chat est venu avec inclinaison de la tête à droite et circling. L’absence d’expression des antigènes du virus ne prend pas en charge le diagnositic post mortem e d’une encéphalomyélite pointant vers un lymphome primaire du système nerveux central type T diffus sur la base de CD3 et CD45R coexpression avec absence CD79α expression.(Traduit par les auteurs).

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Figures

Figure 1
Figure 1
Dorsal T1-weighted MR images at the level of the corpus callosum. Compression of the right lateral ventricle in the temporal cortex without formation of a well-defined mass (arrows). L — left side.
Figure 2
Figure 2
Cervical spinal cord. Thick perivascular cuffs together with a diffuse infiltrate of lymphoid cells and gliosis are seen in the white matter. Hematoxylin and eosin (H&E). Bar = 200 μm. (Inset) — Higher magnification of a thick perivascular cuff. H&E. Bar = 50 μm.
Figure 3
Figure 3
Brain. Serial sections of a perivascular cuff area. Note that the same cells are stained in both (A) and (B) (arrows). A — Lymphoid cells displaying a strong membranous and cytoplasmatic staining with CD3 antibody. Peroxidase antiperoxidase immunohistochemical method. Bar = 100 μm. B — Lymphoid cells displaying a strong membranous and cytoplasmatic staining with CD45R antibody. Avidin-biotin peroxidase immunohistochemical method. Bar = 100 μm.
See this image and copyright information in PMC

References

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