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Clinical Trial
. 2013 Sep;54(9):864-8.

Clinical use of a low-dose medetomidine infusion in healthy dogs undergoing ovariohysterectomy

Eva Rioja  1 , Giacomo Gianotti, Alexander Valverde
Affiliations
Clinical Trial

Clinical use of a low-dose medetomidine infusion in healthy dogs undergoing ovariohysterectomy

Eva Rioja et al. Can Vet J. 2013 Sep.

Abstract
in English, French

Eight healthy dogs undergoing elective ovariohysterectomy were anesthetized with a standard protocol and received a low-dose medetomidine constant rate infusion during surgery. Cardiorespiratory parameters, including non-invasive cardiac output, were measured at various times. This protocol resulted in acceptable and stable cardiovascular performance, allowed low isoflurane concentrations, and provided smooth recoveries.

Utilisation clinique d’une infusion d’une faible dose de médétomidine chez les chiennes en santé subissant une ovariohystérectomie. Huit chiennes en santé subissant une ovariohystérectomie non urgente ont été anesthésiées à l’aide d’un protocole standard et ont reçu une infusion constante d’une faible dose de médétomidine durant la chirurgie. Les paramètres cardiorespiratoires, incluant le débit cardiaque non effractif, ont été mesurés à divers moments. Ce protocole a produit un rendement cardiovasculaire acceptable et stable et a permis de faibles concentrations d’isoflurane et des réveils sans problème.(Traduit par Isabelle Vallières).

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Figures

Figure 1
Figure 1
Mean ± SD values of cardiac index (CI), systolic arterial blood pressure (SBP), and heart rate (HR) obtained at various times during anesthesia in dogs undergoing ovariohysterectomy that were anesthetized with isoflurane and received medetomidine (1 μg/kg BW bolus followed by 1 μg/kg BW per hour, IV). T1 — after induction, before medetomidine bolus; T2 — 5 to 10 min after medetomidine bolus and start of medetomidine CRI; T3 — skin incision; T4 and T5 — removal of first and second ovaries, respectively; T6 — closure of abdominal wall; T7 — after skin sutures. * Value significantly different from T1 (P < 0.05).
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References

    1. Ilkiw JE. Balanced anesthetic techniques in dogs and cats. Clin Tech Small Anim Pract. 1999;14:27–37. - PubMed
    1. Sinclair MD. A review of the physiological effects of alpha2-agonists related to the clinical use of medetomidine in small animal practice. Can Vet J. 2003;44:885–897. - PMC - PubMed
    1. Sano T, Nishimura R, Mochizuki M, Sasaki N. Effects of midazolam-butorphanol, acepromazine-butorphanol and medetomidine on an induction dose of propofol and their compatibility in dogs. J Vet Med Sci. 2003;65:1141–1143. - PubMed
    1. Gomez-Villamandos RJ, Palacios C, Benitez A, et al. Effect of medetomidine infusion on the anaesthetic requirements of desflurane in dogs. Res Vet Sci. 2008;84:68–73. - PubMed
    1. Vickery RG, Sheridan BC, Segal IS, Maze M. Anesthetic and hemodynamic effects of the stereoisomers of medetomidine, an alpha 2-adrenergic agonist, in halothane-anesthetized dogs. Anesth Analg. 1988;67:611–615. - PubMed

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