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Clinical Trial
. 2013 Sep;54(9):864-8.

Clinical use of a low-dose medetomidine infusion in healthy dogs undergoing ovariohysterectomy

Eva Rioja  1 , Giacomo Gianotti, Alexander Valverde
Affiliations
Clinical Trial

Clinical use of a low-dose medetomidine infusion in healthy dogs undergoing ovariohysterectomy

Eva Rioja et al. Can Vet J. 2013 Sep.

Abstract
in English, French

Eight healthy dogs undergoing elective ovariohysterectomy were anesthetized with a standard protocol and received a low-dose medetomidine constant rate infusion during surgery. Cardiorespiratory parameters, including non-invasive cardiac output, were measured at various times. This protocol resulted in acceptable and stable cardiovascular performance, allowed low isoflurane concentrations, and provided smooth recoveries.

Utilisation clinique d’une infusion d’une faible dose de médétomidine chez les chiennes en santé subissant une ovariohystérectomie. Huit chiennes en santé subissant une ovariohystérectomie non urgente ont été anesthésiées à l’aide d’un protocole standard et ont reçu une infusion constante d’une faible dose de médétomidine durant la chirurgie. Les paramètres cardiorespiratoires, incluant le débit cardiaque non effractif, ont été mesurés à divers moments. Ce protocole a produit un rendement cardiovasculaire acceptable et stable et a permis de faibles concentrations d’isoflurane et des réveils sans problème.(Traduit par Isabelle Vallières).

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Figures

Figure 1
Figure 1
Mean ± SD values of cardiac index (CI), systolic arterial blood pressure (SBP), and heart rate (HR) obtained at various times during anesthesia in dogs undergoing ovariohysterectomy that were anesthetized with isoflurane and received medetomidine (1 μg/kg BW bolus followed by 1 μg/kg BW per hour, IV). T1 — after induction, before medetomidine bolus; T2 — 5 to 10 min after medetomidine bolus and start of medetomidine CRI; T3 — skin incision; T4 and T5 — removal of first and second ovaries, respectively; T6 — closure of abdominal wall; T7 — after skin sutures. * Value significantly different from T1 (P < 0.05).
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