Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985 Dec 1;162(6):2175-9.
doi: 10.1084/jem.162.6.2175.

bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia

C R Bartram

bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia

C R Bartram. J Exp Med. .

Abstract

Southern blot analysis detected a bcr gene rearrangement within leukemic cells of a Philadelphia chromosome-negative chronic myelocytic leukemia (CML) patient that led to transcription of a novel 7.3 kb bcr RNA species. Participation of the c-abl oncogene in this genomic recombination could be ruled out by in situ hybridization studies and Northern blot analysis.

PubMed Disclaimer

References

    1. Science. 1973 Mar 16;179(4078):1126-9 - PubMed
    1. Nature. 1973 Jun 1;243(5405):290-3 - PubMed
    1. Eur J Biochem. 1980 Jun;107(2):303-14 - PubMed
    1. Hum Pathol. 1981 Jun;12(6):494-503 - PubMed
    1. Nature. 1982 Dec 23;300(5894):765-7 - PubMed

Publication types