Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Jan 5:722:172-9.
doi: 10.1016/j.ejphar.2013.09.071. Epub 2013 Oct 21.

Anticipatory nausea and vomiting due to chemotherapy

Charles Kamen  1 , Mohamedtaki A Tejani  2 , Kavita Chandwani  2 , Michelle Janelsins  2 , Anita R Peoples  2 , Joseph A Roscoe  2 , Gary R Morrow  2
Affiliations
Review

Anticipatory nausea and vomiting due to chemotherapy

Charles Kamen et al. Eur J Pharmacol. .

Abstract

As a specific variation of chemotherapy-induced nausea and vomiting, anticipatory nausea and vomiting (ANV) appears particularly linked to psychological processes. The three predominant factors related to ANV are classical conditioning; demographic and treatment-related factors; and anxiety or negative expectancies. Laboratory models have provided some support for these underlying mechanisms for ANV. ANV may be treated with medical or pharmacological interventions, including benzodiazepines and other psychotropic medications. However, behavioral treatments, including systematic desensitization, remain first line options for addressing ANV. Some complementary treatment approaches have shown promise in reducing ANV symptoms. Additional research into these approaches is needed. This review will address the underlying models of ANV and provide a discussion of these various treatment options.

Keywords: Anticipatory nausea and vomiting; Behavioral treatments; Cancer; Nausea; Vomiting.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Graphical representation of the development of ANV
See this image and copyright information in PMC

References

    1. Alkaissi A, Stalnert M, Kalman S. Effect and placebo effect of acupressure (P6) on nausea and vomiting after outpatient gynaecological surgery. Acta Anaesthesiologica Scandinavica. 1999;43(3):270–4. - PubMed
    1. Andrykowski MA. The role of anxiety in the development of anticipatory nausea in cancer chemotherapy: A review and synthesis. Psychosomatic Medicine. 1990;52:458–475. - PubMed
    1. Arakawa S. Relaxation to reduce nausea, vomiting, and anxiety induced by chemotherapy in Japanese patients. Cancer Nursing. 1997;20(5):342–349. - PubMed
    1. Barsky AJ, Saintfort R, Rogers MP, Borus JF. Nonspecific medication side effects and the nocebo phenomenon. JAMA. 2002;287:622–7. - PubMed
    1. Bergkvist Karin, Wengstrom Yvonne. Symptom experiences during chemotherapy treatment--with focus on nausea and vomiting. European Journal of Oncology Nursing. 2006;10(1):21–29. - PubMed

MeSH terms