Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2014 Apr;38(4):825-30.
doi: 10.1007/s00264-013-2151-7. Epub 2013 Oct 26.

Clinical outcomes of Kyocera Modular Limb Salvage system after resection of bone sarcoma of the distal part of the femur: the Japanese Musculoskeletal Oncology Group study

Tomoki Nakamura  1 , Akihiko Matsumine, Atsumasa Uchida, Akira Kawai, Yoshihiro Nishida, Toshiyuki Kunisada, Nobuhito Araki, Hideshi Sugiura, Masato Tomita, Masahiro Yokouchi, Takafumi Ueda, Akihiro Sudo
Affiliations
Multicenter Study

Clinical outcomes of Kyocera Modular Limb Salvage system after resection of bone sarcoma of the distal part of the femur: the Japanese Musculoskeletal Oncology Group study

Tomoki Nakamura et al. Int Orthop. 2014 Apr.

Abstract

Purpose: The Japanese Musculoskeletal Oncology Group have developed an original prosthesis called the Kyocera Modular Limb Salvage system (KMLS system). This prosthesis has a semi-rotating hinge joint and is particularly designed for people with an Asian body type. The metallic parts of the prosthesis are made entirely of titanium alloy. The purpose of this study is to evaluate the clinical outcomes of treatment using this system following tumour resection of primary bone sarcoma of the distal femur.

Methods: Between 2002 and 2010, 82 patients with primary bone sarcomas of the distal femur were treated. Seventeen patients underwent stem cementation, while 65 patients were treated with cementless prostheses. The mean follow-up period after surgery was 61 months.

Results: Complications were observed in 28 of the 82 patients. Forty-one complications occurred in these 28 patients. Thirteen prostheses (16%) required revision surgery due to complications, including five cases of stem breakage, three deep infections, three cases of aseptic loosening, one case of displacement of the shaft cap and one case of breakage of the tibial tray. The five-year overall prosthetic survival rate was 80.0%. Four of the 82 patients underwent subsequent amputation due to local recurrence. The five-year limb salvage rate was 94.5%. The mean function score according to the scoring system of the Musculoskeletal Tumour Society was 21.8 points (72.5%).

Conclusions: Although further follow-up is required to determine the performance, this prosthesis is considered to be satisfactory for reconstruction of the distal femur after resection of bone sarcoma.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
The detailed features of the KMLS system. Left Cement-type femoral stem and cementless-type femoral stem and prosthesis. Right Three unique partial-holes and a side plate with three screw holes of the cementless-type femoral stem component
Fig. 2
Fig. 2
Kaplan-Meier curve showing prosthetic survival rate in the 82 patients
Fig. 3
Fig. 3
Kaplan-Meier curve showing limb salvage rate in the 82 patients
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Torbert JT, Fox EJ, Hosalkar HS, Ogilvie CM, Lackman RD. Endoprosthetic reconstructions. Results of long-term follow up of 139 patients. Clin Orthop Relat Res. 2005;438:51–59. doi: 10.1097/01.blo.0000179735.37089.c2. - DOI - PubMed
    1. Dofman HD, Czerniak B. General considerations. In: Dorfman HD, Czerniak B, editors. Bone Tumors. St Louis: CV Mosby; 1988. pp. 1–33.
    1. Matsumine A, Ueda T, Sugita T, et al. Japanese musculoskeletal oncology group. Clinical outcomes of the KYOCERA Physio Hinge total knee system type III after resection of a bone and soft tissue tumor of the distal part of the femur. J Surg Oncol. 2011;103:257–263. doi: 10.1002/jso.21823. - DOI - PubMed
    1. Horowitz SM, Lane JM, Otis JC, Healy JH. Prosthetic arthroplasty of the knee after resection of a sarcoma in the proximal end of the tibia: a report of sixteen cases. J Bone Joint Surg Am. 1991;73-A:286–293. - PubMed
    1. Unwin PS, Cannon SR, Grimer RJ, et al. Aseptic loosening in cemented custom-made replacements for bone tumors of the lower limb. J Bone Joint Surg Br. 1996;78-B:5–13. - PubMed

Publication types