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Comment
. 2013 Nov;62(11):3663-5.
doi: 10.2337/db13-1175.

How does pioglitazone prevent progression of impaired glucose tolerance to diabetes?

Saul M Genuth  1
Affiliations
Comment

How does pioglitazone prevent progression of impaired glucose tolerance to diabetes?

Saul M Genuth. Diabetes. 2013 Nov.
No abstract available

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Figures

FIG. 1.
FIG. 1.
Established and speculative beneficial effects of PIO.
See this image and copyright information in PMC

Comment on

  • Prevention of diabetes with pioglitazone in ACT NOW: physiologic correlates.
    Defronzo RA, Tripathy D, Schwenke DC, Banerji M, Bray GA, Buchanan TA, Clement SC, Gastaldelli A, Henry RR, Kitabchi AE, Mudaliar S, Ratner RE, Stentz FB, Musi N, Reaven PD; ACT NOW Study. Defronzo RA, et al. Diabetes. 2013 Nov;62(11):3920-6. doi: 10.2337/db13-0265. Epub 2013 Jul 17. Diabetes. 2013. PMID: 23863810 Free PMC article. Clinical Trial.

References

    1. Laakso M. Hyperglycemia and cardiovascular disease in type 2 diabetes. Diabetes 1999;48:937–942 - PubMed
    1. Wilson PW. Diabetes mellitus and coronary heart disease. Endocrinol Metab Clin North Am 2001;30:857–881 - PubMed
    1. Stamler J, Vaccaro O, Neaton JD, Wentworth D. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care 1993;16:434–444 - PubMed
    1. Khaw KT, Wareham N, Bingham S, Luben R, Welch A, Day N. Association of hemoglobin A1c with cardiovascular disease and mortality in adults: the European prospective investigation into cancer in Norfolk. Ann Intern Med 2004;141:413–420 - PubMed
    1. Ford ES, Zhao G, Li C. Pre-diabetes and the risk for cardiovascular disease: a systematic review of the evidence. J Am Coll Cardiol 2010;55:1310–1317 - PubMed