Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jun;1(2):122-128.
doi: 10.1007/s40142-013-0014-6.

Biobanking: The Melding of Research with Clinical Care

Maureen E Smith  1 , Sharon Aufox
Affiliations

Biobanking: The Melding of Research with Clinical Care

Maureen E Smith et al. Curr Genet Med Rep. 2013 Jun.

Abstract

The number of biobanks around the world has increased dramatically, owing in part, to the need for researchers to have access to large numbers of samples for genomic research. Policies for enrolling participants, returning research results and obtaining samples and data can have a far reaching impact on the type of research that can be performed with each biobank. Research using biobank samples includes studies of the impact of environmental and other risk exposures on health, understanding genetic risks for common disease, identification of biomarkers in disease progression and prognosis, and implementation of personalized medicine projects. This research has been instrumental in the progress of genetic and genomic research and translational medicine. This article will highlight some of the controversies and recent research associated with biobanking over the past year.

Keywords: Biobank; Biobanking; Genetic; Genetic Research; Genomics; Research Results; Translational Medicine.

PubMed Disclaimer

References

    1. The International Multiple Sclerosis Genetics Consortium (IMSGC) WTCCCW. Sawcer Stephen, et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature. 2011;476:214–9. - PMC - PubMed
    1. Tomlinson IP, Dunlop M, Campbell H, et al. COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer. British journal of cancer. 2010;102:447–54. - PMC - PubMed
    1. Akamatsu S, Takahashi A, Takata R, et al. Reproducibility, performance, and clinical utility of a genetic risk prediction model for prostate cancer in Japanese. PloS one. 2012;7:e46454. - PMC - PubMed
    1. Birdwell KA, Grady B, Choi L, et al. The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients. Pharmacogenet Genomics. 2012;22:32–42. - PMC - PubMed
    1. Le Saux O, Urban Z, Tschuch C, et al. Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum. Nat Genet. 2000;25:223–7. - PubMed

LinkOut - more resources