Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985 Dec 20;230(4732):1375-8.
doi: 10.1126/science.2416056.

A new class of steroids inhibits angiogenesis in the presence of heparin or a heparin fragment

R Crum, S Szabo, J Folkman

A new class of steroids inhibits angiogenesis in the presence of heparin or a heparin fragment

R Crum et al. Science. .

Abstract

Steroids that lack glucocorticoid or mineralocorticoid activity were found to inhibit angiogenesis in the presence of heparin or specific heparin fragments. This newly discovered steroid function appears to be governed by distinct structural configurations of the pregnane nucleus. These compounds are here named angiostatic steroids.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources