Odontogenic myxoma

Abstract

Odontogenic myxoma is a rare intraosseous neoplasm, which is benign but locally aggressive. It rarely appears in any bone other than the jaws. It is considered to be derived from the mesenchymal portion of the tooth germ. Clinically, it is a slow-growing, expansile, painless, non-metastasizing, central tumor of jaws, chiefly the mandible. Here we report the case of a typical odontogenic myxoma in a 26-year-old female patient, which had acquired large dimensions and involved the entire left half of the mandible including the ramus, resulting in a gross facial deformity, within a span of one and a half years.

Keywords: Aggressive; mesenchymal; myxoid; myxoma; odontogenic.

Figure 1

Extraoral view showing a diffuse swelling on the left body region resulting in a slight facial asymmetry

Figure 2

Intraoral view showing swelling at left buccal as well as lingual vestibular region, extending from 34 to 37 region, with displacement of 35 and 36

Figure 3

OPG showing a poorly defined multilocular radiolucency, extending from the midline to left ramus region causing cortical expansion and displacement of 34, 35 and 36 as well as root resorption of 34, 35, 36, 37 and 38

Figure 4

Low-power photomicrograph illustrating loosely arranged stellate-shaped cells with few collagen fibrils and capillaries (H and E ×10)

Figure 5

High-power photomicrograph showing loosely arranged stellate-shaped cells with intermingled fibrillar processes in a homogenous mucoid ground substance (H and E ×40)