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. 1985 Dec 15;41(12):1579-84.
doi: 10.1007/BF01964817.

Cytotoxicity of human peripheral blood T-lymphocyte clones activated by hepatitis B virus surface antigen

A A Hakim

Cytotoxicity of human peripheral blood T-lymphocyte clones activated by hepatitis B virus surface antigen

A A Hakim. Experientia. .

Retraction in

  • Notice of retraction.
    [No authors listed] [No authors listed] Experientia. 1990 May 15;46(5):preceding 429. Experientia. 1990. PMID: 2189745 No abstract available.

Abstract

The present studies examined the cytotoxic activities of peripheral blood lymphocytes (PBL) from volunteers with (sero-positive) and without (sero-negative) circulating antibodies to hepatitis B virus surface antigen before and 30 days after vaccination with hepatitis B virus surface antigen (HBsAg). Long-term culture of monospecific hepatitis B surface (HBsAg)-responsive T-lymphocytes were isolated and grown in large numbers. The mechanism of T-cell mediated cytolysis, and the identification of the carbohydrate determinants on the surface of these effector cells responsible for the killing effect, are being examined.

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