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Review
. 2014 Feb;63(2):198-202.
doi: 10.1161/HYPERTENSIONAHA.113.02293. Epub 2013 Oct 28.

Angiogenic factors in diagnosis, management, and research in preeclampsia

Sarosh Rana  1 , S Ananth Karumanchi, Marshall D Lindheimer
Affiliations
Review

Angiogenic factors in diagnosis, management, and research in preeclampsia

Sarosh Rana et al. Hypertension. 2014 Feb.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Disclosures: Dr. Karumanchi is a co-inventor on multiple patents for preeclampsia markers and reports service as a consultant to Roche, Siemens, Beckman Coulter, and has financial interest in Aggamin LLC. The remaining authors report no conflicts.

References

    1. Powe CE, Levine RJ, Karumanchi SA. Preeclampsia, a disease of the maternal endothelium: The role of antiangiogenic factors and implications for later cardiovascular disease. Circulation. 2011;123:2856–2869. - PMC - PubMed
    1. Cerdeira AS, Karumanchi SA. Angiogenic factors in preeclampsia and related disorders. Cold Spring Harb Perspect Med. 2012:2. - PMC - PubMed
    1. Maynard SE, Min JY, Merchan J, Lim KH, Li J, Mondal S, Libermann TA, Morgan JP, Sellke FW, Stillman IE, Epstein FH, Sukhatme VP, Karumanchi SA. Excess placental soluble fms-like tyrosine kinase 1 (sflt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. The Journal of clinical investigation. 2003;111:649–658. - PMC - PubMed
    1. Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med. 2004;350:672–683. - PubMed
    1. Chaiworapongsa T, Romero R, Kim YM, Kim GJ, Kim MR, Espinoza J, Bujold E, Goncalves L, Gomez R, Edwin S, Mazor M. Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia. J Matern Fetal Neonatal Med. 2005;17:3–18. - PubMed

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