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. 2014 Aug;142(8):1599-608.
doi: 10.1017/S0950268813002719. Epub 2013 Oct 30.

Source attribution of human campylobacteriosis in Denmark

L Boysen  1 , H Rosenquist  1 , J T Larsson  2 , E M Nielsen  2 , G Sørensen  1 , S Nordentoft  3 , T Hald  1
Affiliations

Source attribution of human campylobacteriosis in Denmark

L Boysen et al. Epidemiol Infect. 2014 Aug.

Abstract

SUMMARY This study assesses the contribution of different sources of human campylobacteriosis in Denmark using two different source-attribution approaches. In total, 794 non-human isolates and 406 isolates from human cases (domestic, travel related, and cases with unknown travel history) were collected. Isolates were characterized by multilocus sequence typing, flaA typing and susceptibility to antibiotics. Both models used indicate that the major burden of human campylobacteriosis in Denmark originates from the domestic broiler chicken reservoir. The second most important reservoir was found to be cattle. The Asymmetric Island model attributed 52% [95% credibility interval (CrI) 37-67] to Danish chicken, 17% (95% CrI 3-33) to imported chicken, and 17% (95% CrI 7-28) to cattle. Similarly, the Campylobacter source-attribution model apportioned 38% (95% CrI 28-47) to Danish chicken, 14% (95% CrI 10-18) to imported chicken, and 16% (95% CrI 7-25) to cattle. The addition of flaA type as an extra discriminatory typing parameter did not change the attribution of cases markedly.

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Figures

Fig. 1.
Fig. 1.
Probability of each human case belonging to each of the included sources (results from the basic Asymmetric Island model). (a) Modelling based on multilocus sequence typing (MLST), (b) modelling based on MLST + flaA. The probability is depicted by colour coding: cattle (dark blue), Danish chicken (red), imported chicken (yellow), turkey (green), duck (cyan), pork (pink).
See this image and copyright information in PMC

References

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