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. 2013 Dec 14;11(46):7991-8.
doi: 10.1039/c3ob41469h.

N-Heterocyclic carbene-catalyzed reactions of C-C unsaturated bonds

Xiang-Yu Chen  1 , Song Ye
Affiliations

N-Heterocyclic carbene-catalyzed reactions of C-C unsaturated bonds

Xiang-Yu Chen et al. Org Biomol Chem. .

Abstract

The N-heterocyclic carbene-catalyzed reactions of C-X (X = O, S, N) unsaturated bonds are well established. However, C-C unsaturated bonds are challenging substrates for NHC-catalyzed reactions. In recent years, several reports have demonstrated that NHC-catalyzed reactions of C-C unsaturated bonds are feasible, including the umpolung of Michael acceptors, the Morita-Baylis-Hillman reaction, and the annulation reactions of vinyl sulfones, nitroalkenes, allenoates and alkynes.

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