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. 2013 Sep 17;5(6):142-55.
doi: 10.5539/gjhs.v5n6p142.

Prevalence of metabolic syndrome in type 2 diabetes mellitus using NCEP-ATPIII, IDF and WHO definition and its agreement in Gwalior Chambal region of Central India

Dhananjay Yadav  1 , Sunil Mahajan, Senthil Kumar Subramanian, Prakash Singh Bisen, Choon Hee Chung, G B K S Prasad
Affiliations

Prevalence of metabolic syndrome in type 2 diabetes mellitus using NCEP-ATPIII, IDF and WHO definition and its agreement in Gwalior Chambal region of Central India

Dhananjay Yadav et al. Glob J Health Sci. .

Abstract

The aim of study was to determine the prevalence of metabolic syndrome (MetS) in people with type 2 diabetes mellitus (T2DM). National Cholesterol Education Program (NCEP) ATPIII Criteria, International Diabetes Federation and the World Health Organization (WHO) definitions were used in quantifying the metabolic syndrome and also the concordance between these three criteria's used for identifying metabolic syndrome.

Methods: This cross-sectional study involved 700 type 2 diabetic subjects from the urban areas of Gwalior Chambal region (Central India). Subjects in the age group of 28- 87 yrs were included in the study. Type I diabetics, pregnant ladies and those with chronic viral and bacterial infections and serious metabolic disorders were excluded from the study. Fasting blood glucose, Blood lipids (T-cholesterol, triglyceride, HDL-cholesterol) were assessed and anthropometry blood pressure were measured from all the subjects.

Results: The Prevalence of metabolic syndrome was found to be 45.8%, 57.7% and 28% following NCEP-ATPIII Criteria, IDF and WHO definitions, respectively. Using all the three definitions the prevalence was higher in women in all age groups. ATP III and IDF criteria showed good agreement (k 0.68) compared to ATP III with WHO (k 0.54) and IDF with WHO (k 0.34) criteria. Highest prevalence was observed following IDF definition.

Conclusions: A good agreement was observed between ATPIII and IDF criteria. Maximum prevalence of Metabolic syndrome was recorded when IDF criteria was followed. NCEP-ATPIII criteria for the diagnosis of MetS and this criterion reflected equal importance to the every variable and showed a good agreement between the different criteria used.

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Figures

Figure 1
Figure 1
The prevalence of metabolic syndrome among type II diabetes mellitus using NCEP-ATPIII, IDF and WHO criteria
Figure 2
Figure 2
Metabolic syndrome in different age group of subjects
Figure 3
Figure 3
Venn diagram showing the overlapping of subjects with metabolic syndrome based on three definitions
Figure 4
Figure 4
Different proportions of positive criteria in MetS subjects using NCEP-ATPIII, IDF & WHO criteria
See this image and copyright information in PMC

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