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. 1985 Nov;10(2-3):147-53.
doi: 10.1016/0165-2427(85)90042-x.

Demonstration of both immunologically unique and common antigenic determinants in Dirofilaria immitis and Toxocara canis using monoclonal antibodies

R A Ott, M Staples, M Weekley, E T Maggio

Demonstration of both immunologically unique and common antigenic determinants in Dirofilaria immitis and Toxocara canis using monoclonal antibodies

R A Ott et al. Vet Immunol Immunopathol. 1985 Nov.

Abstract

Using an ELISA system, the immunological cross-reactivity between D. immitis and T. canis has been, for the first time, examined on an individual clone-by-clone basis. This study offers a definitive demonstration of the presence of immunologically distinguishable species-specific non-crossreactive antigens and the presence of cross-reactive antigens in antigenic extracts obtained from adult D. immitis and T. canis.

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