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. 2013 Sep;17(5):624-30.
doi: 10.4103/0972-124X.119279.

Clinical and radiographical evaluation of a bioresorbable collagen membrane of fish origin in the treatment of periodontal intrabony defects: A preliminary study

B B Santosh Kumar  1 , D R Aruna, Vinayak S Gowda, Sushama R Galagali, R Prashanthy, H Navaneetha
Affiliations

Clinical and radiographical evaluation of a bioresorbable collagen membrane of fish origin in the treatment of periodontal intrabony defects: A preliminary study

B B Santosh Kumar et al. J Indian Soc Periodontol. 2013 Sep.

Abstract

Background: Recently, there has been interest in non-mammalian collagen sources such as fish collagen in periodontal regeneration. In the present study, collagen barrier membrane of fish origin was assessed in the treatment of periodontal intrabony defects.

Materials and methods: Ten systemically healthy chronic periodontitis patients having a paired osseous defect in the mandibular posterior teeth were selected and randomly assigned to receive a collagen membrane (test) or open flap debridement (control) in a split mouth design. Clinical parameters such as Plaque index, Gingival bleeding index, Probing pocket depth, Relative attachment level, and Recession were recorded at baseline, 3, 6, and at 9 months, while radiographic evaluation was done to assess alveolar crestal bone level and percentage of defect fill at 6 and 9 months using autoCAD 2007 software. Student's t test (two-tailed, dependent) was used to find the significance of study parameters on continuous scale. Significance was set at 5% level of significance. Wilcoxon signed rank test was used to find the significance of percentage change of defect fill.

Results: The comparison between the two groups did not show any statistically significant differences in the parameters assessed (P > 0.05) but, within each group, clinical parameters showed statistically significant differences from baseline to 9 months (P < 0.05).

Conclusion: Within the limits of the study, it can be inferred that no significant differences were found either by using collagen membrane of fish origin or open flap debridement in the treatment of periodontal intrabony defects.

Keywords: Barriers; collagen; guided tissue regeneration; intrabony defects; membranes.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Baseline clinical parameters were assessed by using UNC-15 probe on a custom-made acrylic stent in relation to 46
Figure 2
Figure 2
Following incision, a full thickness mucoperiosteal flap was reflected and the defect debridement was done
Figure 3
Figure 3
The collagen barrier membrane was trimmed to the required size and shape and placed over the interproximal vertical defect
Figure 4
Figure 4
Suturing was done using 3-0 silk with a simple interrupted direct loop technique
Figure 5
Figure 5
Postoperative follow up at 9 months in relation to the test site
Figure 6
Figure 6
Radiograph of test site at baseline in relation to 46 and 47
Figure 7
Figure 7
Radiograph of control site at baseline in relation to 36 and 37
Figure 8
Figure 8
Radiograph of test site at 6 months in relation to 46 and 47
Figure 9
Figure 9
Radiograph of control site at 6 months in relation to 36 and 37
Figure 10
Figure 10
Radiograph of test site at 9 months in relation to 46 and 47
Figure 11
Figure 11
Radiograph of control site at 9 months in relation to 36 and 37
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