Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2013 Nov;144(5):639-48.
doi: 10.1016/j.ajodo.2013.06.017.

Effect of micro-osteoperforations on the rate of tooth movement

Mani Alikhani  1 , Markos Raptis, Billie Zoldan, Chinapa Sangsuwon, Yoo B Lee, Bandar Alyami, Corey Corpodian, Luz M Barrera, Sarah Alansari, Edmund Khoo, Cristina Teixeira
Affiliations
Randomized Controlled Trial

Effect of micro-osteoperforations on the rate of tooth movement

Mani Alikhani et al. Am J Orthod Dentofacial Orthop. 2013 Nov.

Abstract

Introduction: Our objectives were to study the effect of micro-osteoperforations on the rate of tooth movement and the expression of inflammatory markers.

Methods: Twenty adults with Class II Division 1 malocclusion were divided into control and experimental groups. The control group did not receive micro-osteoperforations, and the experimental group received micro-osteoperforations on 1 side of the maxilla. Both maxillary canines were retracted, and movement was measured after 28 days. The activity of inflammatory markers was measured in gingival crevicular fluid using an antibody-based protein assay. Pain and discomfort were monitored with a numeric rating scale.

Results: Micro-osteoperforations significantly increased the rate of tooth movement by 2.3-fold; this was accompanied by a significant increase in the levels of inflammatory markers. The patients did not report significant pain or discomfort during or after the procedure, or any other complications.

Conclusions: Micro-osteoperforation is an effective, comfortable, and safe procedure to accelerate tooth movement and significantly reduce the duration of orthodontic treatment.

PubMed Disclaimer

Comment in

  • Effect of micro-osteoperforations.
    Prasad S, Ravindran S. Prasad S, et al. Am J Orthod Dentofacial Orthop. 2014 Mar;145(3):273. doi: 10.1016/j.ajodo.2014.01.003. Am J Orthod Dentofacial Orthop. 2014. PMID: 24582015 No abstract available.
  • Effect of micro-osteoperforations. Authors' response.
    Alikhani M, Raptis M, Zoldan B, Sangsuwon C, Lee YB, Alyami B, Corpodian C, Barrera LM, Alansari S, Khoo E, Teixeira C. Alikhani M, et al. Am J Orthod Dentofacial Orthop. 2014 Mar;145(3):273-4. doi: 10.1016/j.ajodo.2014.01.004. Am J Orthod Dentofacial Orthop. 2014. PMID: 24582016 No abstract available.

Publication types

MeSH terms

LinkOut - more resources