Early diagnosis of invasive pulmonary aspergillosis in hematologic patients: an opportunity to improve the outcome

doi:10.3324/haematol.2013.094359

Editorial

. 2013 Nov;98(11):1657-60.

doi: 10.3324/haematol.2013.094359.

Early diagnosis of invasive pulmonary aspergillosis in hematologic patients: an opportunity to improve the outcome

Marcio Nucci¹, Simone A Nouér, Domenico Cappone, Elias Anaissie

Affiliations

PMID: 24186309
PMCID: PMC3815162
DOI: 10.3324/haematol.2013.094359

Editorial

Early diagnosis of invasive pulmonary aspergillosis in hematologic patients: an opportunity to improve the outcome

Marcio Nucci et al. Haematologica. 2013 Nov.

. 2013 Nov;98(11):1657-60.

doi: 10.3324/haematol.2013.094359.

Authors

Marcio Nucci¹, Simone A Nouér, Domenico Cappone, Elias Anaissie

Affiliation

¹ mnucci@hucff.ufrj.br.

PMID: 24186309
PMCID: PMC3815162
DOI: 10.3324/haematol.2013.094359

No abstract available

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Figures

**Figure 1.**
Evolution of invasive pulmonary aspergillosis in the bronchoalveolar and the angioinvasive phases in neutropenic and non-neutropenic patients.

**Figure 2.**
The clinical evolution of invasive pulmonary aspergillosis. *Lesions evolve to air crescent and cavity when neutrophils recover. BAL: bronchoalveolar lavage.

See this image and copyright information in PMC

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[How I diagnose and treat invasive fungal diseases after hematopoietic stem cell transplantation].
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References

1. Pagano L, Caira M, Candoni A, Offidani M, Martino B, Specchia G, et al. Invasive aspergillosis in patients with acute myeloid leukemia: a SEIFEM-2008 registry study. Haematologica. 2010;95(4):644–50 - PMC - PubMed
1. Nucci M, Garnica M, Gloria AB, Lehugeur DS, Dias VC, Palma LC, et al. Invasive fungal diseases in haematopoietic cell transplant recipients and in patients with acute myeloid leukaemia or myelodysplasia in Brazil. Clin Microbiol Infect. 2013;19(8):745–51 - PubMed
1. Denning DW. Therapeutic outcome in invasive aspergillosis. Clin Infect Dis. 1996;23(3):608–15 - PubMed
1. Maertens J, Buve K, Theunissen K, Meersseman W, Verbeken E, Verhoef G, et al. Galactomannan serves as a surrogate endpoint for outcome of pulmonary invasive aspergillosis in neutropenic hematology patients. Cancer 2009;115(2):355–62 - PubMed
1. Nucci M, Nouer SA, Grazziutti M, Kumar NS, Barlogie B, Anaissie E. Probable invasive aspergillosis without prespecified radiologic findings: proposal for inclusion of a new category of aspergillosis and implications for studying novel therapies. Clin Infect Dis. 2010;51(11):1273–80 - PubMed

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[1] Pagano L, Caira M, Candoni A, Offidani M, Martino B, Specchia G, et al. Invasive aspergillosis in patients with acute myeloid leukemia: a SEIFEM-2008 registry study. Haematologica. 2010;95(4):644–50 - PMC - PubMed

[2] Pagano L, Caira M, Candoni A, Offidani M, Martino B, Specchia G, et al. Invasive aspergillosis in patients with acute myeloid leukemia: a SEIFEM-2008 registry study. Haematologica. 2010;95(4):644–50 - PMC - PubMed

[3] Nucci M, Garnica M, Gloria AB, Lehugeur DS, Dias VC, Palma LC, et al. Invasive fungal diseases in haematopoietic cell transplant recipients and in patients with acute myeloid leukaemia or myelodysplasia in Brazil. Clin Microbiol Infect. 2013;19(8):745–51 - PubMed

[4] Nucci M, Garnica M, Gloria AB, Lehugeur DS, Dias VC, Palma LC, et al. Invasive fungal diseases in haematopoietic cell transplant recipients and in patients with acute myeloid leukaemia or myelodysplasia in Brazil. Clin Microbiol Infect. 2013;19(8):745–51 - PubMed

[5] Denning DW. Therapeutic outcome in invasive aspergillosis. Clin Infect Dis. 1996;23(3):608–15 - PubMed

[6] Denning DW. Therapeutic outcome in invasive aspergillosis. Clin Infect Dis. 1996;23(3):608–15 - PubMed

[7] Maertens J, Buve K, Theunissen K, Meersseman W, Verbeken E, Verhoef G, et al. Galactomannan serves as a surrogate endpoint for outcome of pulmonary invasive aspergillosis in neutropenic hematology patients. Cancer 2009;115(2):355–62 - PubMed

[8] Maertens J, Buve K, Theunissen K, Meersseman W, Verbeken E, Verhoef G, et al. Galactomannan serves as a surrogate endpoint for outcome of pulmonary invasive aspergillosis in neutropenic hematology patients. Cancer 2009;115(2):355–62 - PubMed

[9] Nucci M, Nouer SA, Grazziutti M, Kumar NS, Barlogie B, Anaissie E. Probable invasive aspergillosis without prespecified radiologic findings: proposal for inclusion of a new category of aspergillosis and implications for studying novel therapies. Clin Infect Dis. 2010;51(11):1273–80 - PubMed

[10] Nucci M, Nouer SA, Grazziutti M, Kumar NS, Barlogie B, Anaissie E. Probable invasive aspergillosis without prespecified radiologic findings: proposal for inclusion of a new category of aspergillosis and implications for studying novel therapies. Clin Infect Dis. 2010;51(11):1273–80 - PubMed

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Early diagnosis of invasive pulmonary aspergillosis in hematologic patients: an opportunity to improve the outcome

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Early diagnosis of invasive pulmonary aspergillosis in hematologic patients: an opportunity to improve the outcome

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