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. 2014 Jan;71(1):30-9.
doi: 10.1136/oemed-2013-101597. Epub 2013 Nov 1.

Respiratory disease mortality among US coal miners; results after 37 years of follow-up

Judith M Graber  1 , Leslie T Stayner, Robert A Cohen, Lorraine M Conroy, Michael D Attfield
Affiliations

Respiratory disease mortality among US coal miners; results after 37 years of follow-up

Judith M Graber et al. Occup Environ Med. 2014 Jan.

Erratum in

  • Occup Environ Med. 2014 Oct;71(10):738

Abstract

Objectives: To evaluate respiratory related mortality among underground coal miners after 37 years of follow-up.

Methods: Underlying cause of death for 9033 underground coal miners from 31 US mines enrolled between 1969 and 1971 was evaluated with life table analysis. Cox proportional hazards models were fitted to evaluate the exposure-response relationships between cumulative exposure to coal mine dust and respirable silica and mortality from pneumoconiosis, chronic obstructive pulmonary disease (COPD) and lung cancer.

Results: Excess mortality was observed for pneumoconiosis (SMR=79.70, 95% CI 72.1 to 87.67), COPD (SMR=1.11, 95% CI 0.99 to 1.24) and lung cancer (SMR=1.08; 95% CI 1.00 to 1.18). Coal mine dust exposure increased risk for mortality from pneumoconiosis and COPD. Mortality from COPD was significantly elevated among never [corrected] smokers and former smokers (HR=1.84, 95% CI 1.05 to 3.22; HRK=1.52, 95% CI 0.98 to 2.34, respectively) but not current smokers (HR=0.99, 95% CI 0.76 to 1.28). Respirable silica was positively associated with mortality from pneumoconiosis (HR=1.33, 95% CI 0.94 to 1.33) and COPD (HR=1.04, 95% CI 0.96 to 1.52) in models controlling for coal mine dust. We saw a significant relationship between coal mine dust exposure and lung cancer mortality (HR=1.70; 95% CI 1.02 to 2.83) but not with respirable silica (HR=1.05; 95% CI 0.90 to 1.23). In the most recent follow-up period (2000-2007) both exposures were positively associated with lung cancer mortality, coal mine dust significantly so.

Conclusions: Our findings support previous studies showing that exposure to coal mine dust and respirable silica leads to increased mortality from malignant and non-malignant respiratory diseases even in the absence of smoking.

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Conflict of interest statement

Competing interests None.

Comment in

References

    1. Antao VC, Petsonk EL, Sokolow LZ, et al. Rapidly progressive coal workers’ pneumoconiosis in the United States: geographic clustering and other factors. Occup Environ Med. 2005;62:670–4. - PMC - PubMed
    1. Laney AS, Attfield MD. Coal workers’ pneumoconiosis and progressive massive fibrosis are increasingly more prevalent among workers in small underground coal mines in the United States. Occup Environ Med. 2010;67:428–31. - PubMed
    1. NIOSH. Occupational exposure to respirable coal mine dust. Cincinnati, Ohio; Washington, DC: U.S. Dept. of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health; 1995.
    1. NIOSH. Coal mine dust exposures and associated health outcomes. Washington, DC: National Institute for Occupational Safety and Health; 2011.
    1. Cohen R, Velho V. Update on respiratory disease from coal mine and silica dust. Clin Chest Med. 2002;23:811–26. - PubMed

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