Participatory medicine: A home score for streptococcal pharyngitis enabled by real-time biosurveillance: a cohort study
- PMID: 24189592
- PMCID: PMC3953456
- DOI: 10.7326/0003-4819-159-9-201311050-00003
Participatory medicine: A home score for streptococcal pharyngitis enabled by real-time biosurveillance: a cohort study
Abstract
Background: Consensus guidelines recommend against testing or treating adults at low risk for group A streptococcal (GAS) pharyngitis.
Objective: To help patients decide when to visit a clinician for the evaluation of sore throat.
Design: Retrospective cohort study.
Setting: A national chain of retail health clinics.
Patients: 71 776 patients aged 15 years or older with pharyngitis who visited a clinic from September 2006 to December 2008.
Measurements: The authors created a score using information from patient-reported clinical variables plus the incidence of local disease and compared it with the Centor score and other traditional scores that require clinician-elicited signs.
Results: If patients aged 15 years or older with sore throat did not visit a clinician when the new score estimated the likelihood of GAS pharyngitis to be less than 10% instead of having clinicians manage their symptoms following guidelines that use the Centor score, 230 000 visits would be avoided in the United States each year and 8500 patients with GAS pharyngitis who would have received antibiotics would not be treated with them.
Limitation: Real-time information about the local incidence of GAS pharyngitis, which is necessary to calculate the new score, is not currently available.
Conclusion: A patient-driven approach to pharyngitis diagnosis that uses this new score could save hundreds of thousands of visits annually by identifying patients at home who are unlikely to require testing or treatment.
Primary funding source: Centers for Disease Control and Prevention and the National Library of Medicine, National Institutes of Health.
Conflict of interest statement
Comment in
-
When should patients seek care for sore throat?Ann Intern Med. 2013 Nov 5;159(9):636-7. doi: 10.7326/0003-4819-159-9-201311050-00012. Ann Intern Med. 2013. PMID: 24189598 No abstract available.
-
Streptococcal pharyngitis in adults: can it be efficiently and effectively managed by remote control?Ann Intern Med. 2013 Nov 5;159(9):638-9. doi: 10.7326/0003-4819-159-9-201311050-00013. Ann Intern Med. 2013. PMID: 24189599 No abstract available.
-
Participatory medicine: a home score for streptococcal pharyngitis.Ann Intern Med. 2014 Feb 18;160(4):289. doi: 10.7326/L14-5004. Ann Intern Med. 2014. PMID: 24534927 No abstract available.
-
Participatory medicine: a home score for streptococcal pharyngitis.Ann Intern Med. 2014 Feb 18;160(4):289. doi: 10.7326/L14-5004-2. Ann Intern Med. 2014. PMID: 24534928 No abstract available.
Summary for patients in
-
Summaries for patients. A home score for streptococcal pharyngitis.Ann Intern Med. 2013 Nov 5;159(9):I-24. doi: 10.7326/0003-4819-159-9-201311050-00001. Ann Intern Med. 2013. PMID: 24344367 No abstract available.
Similar articles
-
Improved diagnostic accuracy of group A streptococcal pharyngitis with use of real-time biosurveillance.Ann Intern Med. 2011 Sep 20;155(6):345-52. doi: 10.7326/0003-4819-155-6-201109200-00002. Ann Intern Med. 2011. PMID: 21930851 Free PMC article.
-
Summaries for patients. A home score for streptococcal pharyngitis.Ann Intern Med. 2013 Nov 5;159(9):I-24. doi: 10.7326/0003-4819-159-9-201311050-00001. Ann Intern Med. 2013. PMID: 24344367 No abstract available.
-
Large-scale validation of the Centor and McIsaac scores to predict group A streptococcal pharyngitis.Arch Intern Med. 2012 Jun 11;172(11):847-52. doi: 10.1001/archinternmed.2012.950. Arch Intern Med. 2012. PMID: 22566485 Free PMC article.
-
Predicting streptococcal pharyngitis in adults in primary care: a systematic review of the diagnostic accuracy of symptoms and signs and validation of the Centor score.BMC Med. 2011 Jun 1;9:67. doi: 10.1186/1741-7015-9-67. BMC Med. 2011. PMID: 21631919 Free PMC article.
-
Signs and symptoms of Group A versus Non-Group A strep throat: A meta-analysis.Fam Pract. 2018 May 23;35(3):231-238. doi: 10.1093/fampra/cmx072. Fam Pract. 2018. PMID: 29045629
Cited by
-
Reducing unnecessary antibiotics prescribed to children: what next?Pediatrics. 2014 Mar;133(3):533-4. doi: 10.1542/peds.2013-4016. Epub 2014 Feb 2. Pediatrics. 2014. PMID: 24488739 Free PMC article. No abstract available.
-
Evaluation of symptom checkers for self diagnosis and triage: audit study.BMJ. 2015 Jul 8;351:h3480. doi: 10.1136/bmj.h3480. BMJ. 2015. PMID: 26157077 Free PMC article.
-
Artificial intelligence method to classify ophthalmic emergency severity based on symptoms: a validation study.BMJ Open. 2020 Jul 5;10(7):e037161. doi: 10.1136/bmjopen-2020-037161. BMJ Open. 2020. PMID: 32624476 Free PMC article.
-
Comparison of Centor and McIsaac scores in primary care: a meta-analysis over multiple thresholds.Br J Gen Pract. 2020 Mar 26;70(693):e245-e254. doi: 10.3399/bjgp20X708833. Print 2020 Apr. Br J Gen Pract. 2020. PMID: 32152041 Free PMC article.
-
A feasibility service evaluation of screening and treatment of group A streptococcal pharyngitis in community pharmacies.J Antimicrob Chemother. 2016 Nov;71(11):3293-3299. doi: 10.1093/jac/dkw264. Epub 2016 Jul 20. J Antimicrob Chemother. 2016. PMID: 27439523 Free PMC article.
References
-
- Carapetis JR, Steer AC, Mulholland EK, Weber M. The global burden of group A streptococcal diseases. Lancet Infect Dis. 2005;5:685–94. - PubMed
-
- Klepser DG, Bisanz SE, Klepser ME. Cost-effectiveness of pharmacist-provided treatment of adult pharyngitis. Am J Manag Care. 2012;18:e145–54. - PubMed
-
- Wessels MR. Clinical practice. Streptococcal pharyngitis. N Engl J Med. 2011;364:648–55. - PubMed
-
- Centor RM, Witherspoon JM, Dalton HP, Brody CE, Link K. The diagnosis of strep throat in adults in the emergency room. Med Decis Making. 1981;1:239–46. - PubMed
-
- Snow V, Mottur-Pilson C, Cooper RJ, Hoffman JR American Academy of Family Physicians. Principles of appropriate antibiotic use for acute pharyngitis in adults. Ann Intern Med. 2001;134:506–8. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical