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Comment
. 2013 Dec;9(12):713-4.
doi: 10.1038/nrneph.2013.234. Epub 2013 Nov 5.

Transplantation: Complementing donor-specific antibody testing

Kathryn J Tinckam  1 , Peter S Heeger
Affiliations
Comment

Transplantation: Complementing donor-specific antibody testing

Kathryn J Tinckam et al. Nat Rev Nephrol. 2013 Dec.

Abstract

New data suggest that among kidney transplant recipients, those whose serum contains donor-specific antibodies that bind C1q fare the worst. Although these findings are intriguing, several unanswered questions remain and changing practice to include a C1q binding assay as standard of care in kidney transplantation would be premature.

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Comment on

  • Complement-binding anti-HLA antibodies and kidney-allograft survival.
    Loupy A, Lefaucheur C, Vernerey D, Prugger C, Duong van Huyen JP, Mooney N, Suberbielle C, Frémeaux-Bacchi V, Méjean A, Desgrandchamps F, Anglicheau D, Nochy D, Charron D, Empana JP, Delahousse M, Legendre C, Glotz D, Hill GS, Zeevi A, Jouven X. Loupy A, et al. N Engl J Med. 2013 Sep 26;369(13):1215-26. doi: 10.1056/NEJMoa1302506. N Engl J Med. 2013. PMID: 24066742

References

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