Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1968 Mar;3(2):106-15.
doi: 10.1007/BF01723732.

Inhibition of electron transport enzymes and cholinesterases by Endrin

H J Colvin  1 , A T Phillips
Affiliations

Inhibition of electron transport enzymes and cholinesterases by Endrin

H J Colvin et al. Bull Environ Contam Toxicol. 1968 Mar.

Abstract

Two enzymes involved in mitqchondrial electron transport in the catfish,Ictalurus melas, have been shown to be inhibited by endrin. Succinate dehydrogenase and cytochrome oxidase were both inhibited, and the extent of inhibition depended ypon endrin concentration and the specific activity ef the enzyme preparation. No appreciable effect of endrin on acetylcholinesterase or NADH-cytochrome c reductase was seen. Binding to lipoprotein components essential for mitochondrial oxidation has been proposed as a logical site for endrin action.

PubMed Disclaimer

References

    1. Science. 1966 Aug 12;153(3737):757-9 - PubMed
    1. J Biol Chem. 1949 Aug;180(1):249-61 - PubMed
    1. Biochem Pharmacol. 1961 Jul;7:88-95 - PubMed
    1. Science. 1966 Dec 30;154(3757):1661-2 - PubMed
    1. J Biol Chem. 1951 Nov;193(1):265-75 - PubMed