Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 Mar;165(3):1046-8.
doi: 10.1128/jb.165.3.1046-1048.1986.

Escherichia coli tryptophan operon directs the in vivo synthesis of a leader peptide

L Dekel-Gorodetsky, R Schoulaker-Schwarz, H Engelberg-Kulka

Escherichia coli tryptophan operon directs the in vivo synthesis of a leader peptide

L Dekel-Gorodetsky et al. J Bacteriol. 1986 Mar.

Abstract

Here we report the identification of the Escherichia coli trp leader peptide synthesized in vivo. We identified the peptide in UV-irradiated maxicells by selective labeling with radioactive amino acids which are included in the predicted sequence of this peptide. Our results support the hypothesis that translation of the peptide-coding region of the leader RNA has a role in the mechanism of attenuation of biosynthetic operons in general and in the E. coli trp operon in particular.

PubMed Disclaimer

References

    1. Nature. 1974 Jun 7;249(457):523-7 - PubMed
    1. Proc Natl Acad Sci U S A. 1983 May;80(10):2879-83 - PubMed
    1. Science. 1975 Jul 4;189(4196):22-6 - PubMed
    1. J Mol Biol. 1976 May 15;103(2):411-20 - PubMed
    1. J Mol Biol. 1977 Jan 15;109(2):303-26 - PubMed

Publication types

LinkOut - more resources