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Comparative Study
. 2014 Feb;59(2):446-50.
doi: 10.1007/s10620-013-2898-0. Epub 2013 Nov 6.

Prevalence of colorectal neoplasia among young African Americans and Hispanic Americans

Hassan Ashktorab  1 , Mansour Paydar, Hassan Hassanzadeh Namin, Andrew Sanderson, Rehana Begum, Hassan Brim, Heena Panchal, Edward Lee, Angesom Kibreab, Mehdi Nouraie, Adeyinka O Laiyemo
Affiliations
Comparative Study

Prevalence of colorectal neoplasia among young African Americans and Hispanic Americans

Hassan Ashktorab et al. Dig Dis Sci. 2014 Feb.

Abstract

Background: The disproportionately higher incidence of and mortality from colorectal cancer (CRC) among African Americans (AA) led the American College of Gastroenterology to recommend screening starting at age 45 in 2005.

Aim: The purpose of this study was to determine the prevalence of colorectal neoplasia among 40-49-year-old inner city AA and Hispanic Americans (HA).

Methods: We reviewed the medical records of 2,435 inner city AA and HA who underwent colonoscopy regardless of indication and compared the prevalence of colorectal neoplasia between AA and HA patients. We used logistic regression models to calculate odds ratios (OR) and 95 % confidence intervals (CI).

Results: There were 2,163 AAs and 272 HA. There were 57 % women in both groups. A total of 158 (7 %) AA and 9 (3 %) HA (P = 0.014) underwent the procedures for CRC screening. When compared to HAs, AAs had higher prevalence of any polyp (35 vs. 18 %, OR = 2.53; 95 % CI 1.82-3.52). Overall, AA had higher prevalence of colorectal neoplasia (adenoma and cancer) when compared to HAs (16 vs. 10 %; OR = 1.68; 95 % CI 1.10-2.56).

Conclusion: We observed a higher frequency of colorectal neoplasia among 40-49-year-old AAs as compared to HAs suggesting an increased susceptibility to CRC risk in this population.

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Figures

Figure 1
Figure 1
Percentage of normal (blue) and neoplasia (adenoma and CRC, red) findings by age and race (number in each bar shows the percentage of neoplasia finding in corresponding age and race group).
See this image and copyright information in PMC

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