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Editorial
. 2013 Nov;4(11):1862-3.
doi: 10.18632/oncotarget.1563.

Hexokinase 2 as oncotarget

Krushna C Patra  1 , Nissim Hay
Affiliations
Editorial

Hexokinase 2 as oncotarget

Krushna C Patra et al. Oncotarget. 2013 Nov.
No abstract available

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Figures

Figure 1
Figure 1. A cartoon depicting HK2 is required for glucose and glutamine metabolism in tumor cells
The metabolic pathways inside the cells are like cogwheels inside a machine, controlled by a propelling wheel. In cancer cells, HK2 is a major propelling wheel in glucose metabolism to support accelerated ribonucleotide synthesis and glutamine utilization in the TCA cycle, and to fulfill anabolic demands. HK2 ablation decelerates these pathways resulting in an attenuated tumor growth.
See this image and copyright information in PMC

References

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