Immune response in severe infection: could life-saving drugs be potentially harmful?
- PMID: 24198733
- PMCID: PMC3806431
- DOI: 10.1155/2013/961852
Immune response in severe infection: could life-saving drugs be potentially harmful?
Abstract
Critically ill patients suffer a high rate of nosocomial infection with secondary sepsis being a common cause of death. Usage of antibiotics and catecholamines is often necessary, but it can compromise complex immune response to infection. This review explores influence of these life-saving drugs on host immune response to severe infection.
References
-
- Surbatovic M, Radakovic S, Jovanovic K, et al. New strategies in multiple organ dysfunction syndrome therapy for sepsis. Srpski Arhiv za Celokupno Lekarstvo. 2005;133:379–383. - PubMed
-
- Surbatovic M, Filipovic N, Slavkovic Z, et al. Infection and inflammation in sepsis. Vojnosanitetski Pregled. 2006;63:163–168. - PubMed
-
- Djordjevic D, Surbatovic M, Ugrinovic D, et al. New aspects of sepsis pathophysiology in critically ill. Vojnosanitetski Pregled. 2012;69:58–68. - PubMed
-
- Surbatovic M, Filipovic N, Army S, Radakovic S, Stankovic N, Slavkovic Z. Immune cytokine response in combat casualties: blast or explosive trauma with or without secondary sepsis. Military Medicine. 2007;172(2):190–195. - PubMed
-
- Ulloa L, Tracey KJ. The “cytokine profile”: a code for sepsis. Trends in Molecular Medicine. 2005;11(2):56–63. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources