Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Nov 7:13:294.
doi: 10.1186/1471-244X-13-294.

Resistance to treatment and change in anorexia nervosa [corrected]: a clinical overview

Affiliations

Resistance to treatment and change in anorexia nervosa [corrected]: a clinical overview

Giovanni Abbate-Daga et al. BMC Psychiatry. .

Erratum in

  • BMC Psychiatry. 2014;14:62

Abstract

Background: Current literature on Eating Disorders (EDs) is devoid of evidence-based findings providing support to effective treatments, mostly for anorexia nervosa (AN). This lack of successful guidelines may play a role in making these disorders even more resistant. In fact, many individuals do not respond to the available treatments and develop an enduring and disabling illness. With this overview we aimed to highlight and discuss treatment resistance in AN--with an in-depth investigation of resistance-related psychological factors.A literature search was conducted on PubMed and PsychINFO; English-language articles published between 1990 and 2013 investigating the phenomenon of resistance to treatment in AN have been considered.

Discussion: The selected papers have been then grouped into four main thematic areas: denial of illness; motivation to change; maintaining factors and treatment outcome; and therapeutic relationship. Eating symptomatology was found to only partially explain resistance to treatment. The role of duration of illness has been questioned whilst some maintaining factors seemed promising in providing a useful framework for this phenomenon. Emotive and relational aspects have been investigated on their role in resistance as well as therapists' countertransference.

Summary: Remarkably there has been little research done on resistance to treatment in the ED field, in spite of its clinical relevance. Motivation, insight and subjective meaning of the illness can be useful tools to manage the resistance phenomenon when coupled with a wider approach. The latter enables the therapists to be aware of their role in the therapeutic alliance through countertransference aspects and to consider the EDs as disorders of the development of both personality and self, entailing severe impairments as regards identity and relationships.

PubMed Disclaimer

References

    1. Posse PR, Nemeroff CB. In: Management of treatment-resistant major psychiatric disorders. Nemeroff CB, editor. Oxford: Oxford University Press; 2012. The problem of treatment-resistant major psychiatric disorders; pp. 3–22.
    1. Gabbard GO. In: Management of treatment-resistant major psychiatric disorders. Nemeroff CB, editor. Oxford: Oxford University Press; 2012. Treatment resistance in Personality Disorders; pp. 265–284.
    1. Klump KL, Bulik CM, Kaye WH, Treasure J, Tyson E. Academy for eating disorders position paper: eating disorders are serious mental illnesses. Int J Eat Disord. 2009;13:97–103. - PubMed
    1. Karwautz AF, Wagner G, Waldherr K, Nader IW, Fernandez-Aranda F, Estivill X, Holliday J, Collier DA, Treasure JL. Gene-environment interaction in anorexia nervosa: relevance of non-shared environment and the serotonin transporter gene. Mol Psychiatry. 2011;13:590–592. - PubMed
    1. Kaye W. Eating disorders: hope despite mortal risk. Am J Psychiatry. 2009;13:1309–1311. - PubMed