Cilium assembly: delivery of tubulin by kinesin-2-powered trains
- PMID: 24200322
- DOI: 10.1016/j.cub.2013.09.032
Cilium assembly: delivery of tubulin by kinesin-2-powered trains
Abstract
The kinesin-2-driven anterograde transport of intraflagellar transport (IFT) trains has long been suspected to deliver cargo consisting of tubulin subunits for assembly at the axoneme tip. Important new work identifies the tubulin binding site on IFT trains that is responsible for this cargo transport.
Copyright © 2013 Elsevier Ltd. All rights reserved.
Comment on
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Molecular basis of tubulin transport within the cilium by IFT74 and IFT81.Science. 2013 Aug 30;341(6149):1009-12. doi: 10.1126/science.1240985. Science. 2013. PMID: 23990561 Free PMC article.
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